Course Description

Physiological Science 121: Disease Mechanisms and Therapies, PHYSCI 121

Lecture, three hours; discussion, one hour. Requisites: Chemistry 153A, and Life Sciences 2, 3, and 4 or 7A, 7B, and 7C. Designed for junior/senior Biochemistry and life sciences majors. Use of disease mechanisms as pedagogical tools to develop higher-order knowledge of basic scientific concepts. Integration of concepts from genetics, molecular and cell biology, physiology, and biochemistry to create molecular solutions to problem of inherited neuromuscular disease. Letter grading.

Key Information

Credit: 5 quarter units / 3.33 semester units credit
UC Los Angeles, Integrative Biology and Physiology

Course Credit:

Upon successful completion, all online courses offered through cross-enrollment provide UC unit credit. Some courses are approved for GE, major preparation and/or, major credit or can be used as a substitute for a course at your campus.

If "unit credit" is listed by your campus, consult your department, academic adviser or Student Affairs division to inquire about the petition process for more than unit credit for the course.

UC Berkeley:
Unit Credit

UC Davis:
Unit Credit

UC Irvine:
Major Requirement: Upper Division Elective Credit Biology Major

UC Los Angeles:
Major Requirement: Satisfy upper division elective required for all life sciences and biochemistry majors, electives that are required for MS and PhD programs in the life sciences and biochemistry majors, nursing and other professional students

UC Merced:
Major Requirement: Upper Division BIOS course credit for BIOS tracks: Developmental Biology, Human Biology, Microbiology & Immunology, and Molecular & Cell Biology
Units toward degree (see your adviser)

UC Riverside:
General Education: Elective Units

UC San Diego:
General Education: Warren -  May be counted depending on major/PofC, Transfer students may use for UD noncontiguous GE depending on major; TMC 1 course toward upper division disciplinary breadth if noncontiguous to major; Sixth - 1 Analytic Methodologies/Scientific Method
Major Requirement: Can be applied as an upper-division elective for any Biology major;

UC San Francisco:
Unit Credit

UC Santa Barbara:
Unit Credit

UC Santa Cruz:
General Education: SI

Prerequisites

Enforced requisites: Life Sciences 2, 3, AND 4. Minimum Grade: D-. Designed for Biochemistry and life sciences majors.

Course Fees

Proctor U will be used for the midterm and final.

More About The Course

The goal of this course is to bring undergraduates into the real world of scientific research, therapy design, and clinical application. Students develop an understanding of personalized medicine and are able to apply that knowledge to other diseases and evaluate proposed therapeutic approaches to disease. The class is focused on using disease mechanisms as a pedagogical tool to develop higher order knowledge of basic scientific concepts since students are tasked with integrating concepts from genetics, molecular and cell biology, physiology, and biochemistry in order to create molecular ‘solutions’ to the ‘problem’ of inherited neuromuscular disease. Students in the life science and biochemistry majors are interested in human disease and the pursuit of professional degrees in medicine, nursing, pharmacology, physical therapy, patent/medicinal law, teaching, and research. The course appeals strongly to students’ professional goals and will advance their skills in each of these fields.

Relevant Website

Course Creator

R.H. Crosbie
Dr. Crosbie-Watson is a UCLA Professor and Chair of the Department of Integrative Biology and Physiology with a joint appointment in the David Geffen School of Medicine Department of Neurology. She is the Education Liaison for the UCLA Center for Duchenne Muscular Dystrophy.  She won the 2013 Chancellor's Distinguished Teaching Award for the innovations in teaching that were developed for the face-to-face version of PS121. Dr. Crosbie-Watson conducts research on disease mechanisms and therapies for Duchenne muscular dystrophy. Dr. Crosbie-Watson is a UCLA Professor and Chair of the Department of Integrative Biology and Physiology with a joint appointment in the David Geffen School of Medicine Department of Neurology. She is the Education Liaison for the UCLA Center for Duchenne Muscular Dystrophy.  She won the 2013 Chancellor's Distinguished Teaching Award for the innovations in teaching that were developed for ...

Dr. Crosbie-Watson is a UCLA Professor and Chair of the Department of Integrative Biology and Physiology with a joint appointment in the David Geffen School of Medicine Department of Neurology. She is the Education Liaison for the UCLA Center for Duchenne Muscular Dystrophy.  She won the 2013 Chancellor's Distinguished Teaching Award for the innovations in teaching that were developed for the face-to-face version of PS121. Dr. Crosbie-Watson conducts research on disease mechanisms and therapies for Duchenne muscular dystrophy.

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